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HPE ProLiant DL380 Gen10 Plus Server - System Overview


HPE DL380 Gen10 Plus side view

Designed to meet the needs of virtual desktop infrastructure, software-defined storage (SDS) and high-performance computing (HPC) workloads, the HPE ProLiant DL385 Gen10 Plus provides security and dense deployment for space-constrained environments. Outfitted with dual 1st or 2nd Generation AMD EPYC 7000 Series Processors, it supports PCIe 4.0 slots allowing for greater expansion of the system capabilities. Up to 8TB of memory can be installed on this system.


The 3rd generation Intel Xeon Scalable processors require a different socket than the previous 1st and 2nd generation, which explains the lack of compatibility with the previous generations. However, this 3rd generation includes more cores across the various families with Platinum supporting up to 40 cores, Gold up to 32 cores, and Silver processors delivering up to 20 cores. PCIe 4.0 is now supported with CPUs delivering 64 PCIe lanes each, for 128 PCIe 4.0 lanes in a dual processor configuration. Memory density has also increased with 8x memory channels, up from the previous count of only 6x memory channels on previous generations. Faster memory is also supported at up to 3200MT/s.


There are many storage configurations on the HPE ProLiant DL380 Gen10 Plus Server supporting 3.5-inch and 2.5-inch drive types. Configurations using 2.5-inch drives include 8, 10, 16, 18, or 24 SAS, SATA and SSD storage formats. 20x NVMe drives is another option available via the Express Bay but will limit the drive capacity depending on the specific configuration. Additionally, 3.5-inch LFF configurations include 8x or 12 SAS, SATA and SSD storage devices. Optional 8x SFF and 4x SFF mid-tray drive support, plus various optional rear drive trays supporting either LFF, SFF or UFF drive formats are available significantly increasing storage potential. UFF drives feature a small form factor 2.5-inch drive tray adapter outfitted with 2x Micro Form Factor SATA drives. 2x M.2 SATA drive slots are standard equipment on the primary riser depending on the configuration. A Smart Array controller has a dedicated spot on the motherboard, preserving the PCIe slots. Maximum internal storage of up to 550.8TB is provided with24x 2.5-inch drives up front plus 8x drives in the mid-tray, and 4x drives in a rear-mounted drive tray. Optional drive trays may require the addition of low-profile heatsinks, and high-performance fan modules in all fan bays. Gen 10 Plus Smart Array, MegaRAID, and Tri-Mode controllers, can be installed providing support for SAS drive formats and more control over your storage options. NVMe RAID options are made possible using the Tri-Mode storage controllers. The system includes a built-in Smart Array SR150 Gen10 controller that provides software RAID that will operate in UEFI mode only.


A maximum memory capacity of up to 11.2TB is achieved using a combination of 8x 512GB Data Centric Persistent Memory Modules (DCPMM) paired with 8x 128GB DDR4 Load-Reduced (LRDIMM) memory modules per socket. Each socket has 16x memory module slots for a total of 32x active memory module slots with both processors installed. Using just Registered memory modules, it will support a maximum capacity of up to 8.1TB with 4.05TB of memory per socket. Memory speeds of up to 3200MT/s second are supported on the HPE DL380 Gen10 Plus Server depending on CPU, memory type, and memory configuration.


HPE DL380 Gen10 Plus rear detail view

There are up to 8x PCIe 4.0 slots housed in the Primary, Secondary, and Tertiary risers. The Primary and Secondary risers each have 3x different slot options, and each supporting either all x16 slots with x16 Bus widths or one with x16 connector width and a mix of x16 and x8 bus widths. The Tertiary riser has two options. One has 2x x16 slots with x8 Bus widths and the other has a single x16 slot with a x16 Bus width. An Intel I350 controller offers 1GbE 4-port Base-T OCP3 Adapter or a Broadcom 10GbE 2-port Base-T adapter. However, other optional network controllers are available.


HPE’s proprietary integrated Lights Out (iLO) 5.0 Standard with Intelligent Provisioning is and embedded technology that is included with the purchase. It provides basic tools for managing the system. Standard offers remote console support with an intuitive HTML5 interface that can be accessed through a standard browser with a user name and passcode. ILO 5.0 Standard can also be upgraded to iLO 5.0 Advanced with the purchase of a software license key to provide more management functionality. HPE Infosight offers another level of server management in the data-center simplifying and optimizing data center operations with AI-powered data center operations.


Offering a wealth of security and management features, the HPE ProLiant DL380 Gen10 Plus Server is a fit for either a local network or the data center. The versatile and flexible system features several storage options for speed and resiliency plus extensive expansion capabilities, and a large memory footprint, all powered by dual 3rd generation Intel Xeon Scalable processors.

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HPE ProLiant DL380 Gen10 Plus Server - Specifications

Processor - 2 sockets
  • 3rd Generation Intel Xeon Scalable Processors
    Memory Capacity

  • 32 x DIMM slots
  • 8.1 TB - RDIMM (4 TB per processor)
  • 11.2 TB - LRDIMM and Intel Optane (5.6 TB per processor with 8x LRDIMM and 8x 512 GB Intel Optane)

  • Optional: Intel® Optane™ Persistent Memory for HPE
  • Capacity: 128GB - 512GB
Drive Bays
  • 8 or 12 x LFF SAS/SATA/SSD
  • 8, 10, 16, 18 or 24 x SFF SAS/SATA/SSD
  • 2 M.2 SATA SSD standard on primary riser
  • Optional Drive Bay configurations:

  • 8 x SFF mid-tray
  • 6 x SFF rear drive optional
  • 4 x LFF mid tray optional
  • 3 x LFF rear-drive optional
  • 2 SFF or 2 Dual UFF rear-drive optional
  • 20 x SFF NVMe optional
I/O Ports

  • Optional, rear
  • Display Port

  • 1 x optional front display port via Universal Media Bay
  • VGA Port

  • 1 x Standard, rear for all chassis
  • Network Ports

  • None. Choice of OCP networking card or stand-up networking card required. BTO models will come pre-selected with a primary OCP networking card.
  • HPE iLO Remote Management Network Port

  • 1 Gb, Dedicated
  • Front iLO Service Port

  • 1 standard (Not available on 12 LFF chassis or when SID is ordered, note iLO dongle required. Hewlett Packard Enterprise recommends the HPE USB to Ethernet Adapter (part number Q7Y55A)
  • Micro SD Slot

  • Optional via HPE 32GB microSD RAID1 USB Boot Device
  • USB 3.0

  • Up to 5 total: 1 front, 2 rear, 2 internal (secure), 2 optional USB 2.0 front via Universal Media Bay, or standard on 8LFF chassis
  • SID (Systems Insight Display)

  • Optional
    Form Factor

  • 2U
  • Weight

  • 8 SFF Drives: 63.43lbs (28.77kg)
  • 12 LFF Drives: 74.94lbs (33.99kg)
  • Product Dimensions

  • SFF: 3.44in x 17.54in x 28in (8.75cm x 44.54cm x 71cm)
  • LFF: 3.44in x 17.54in x 29.5in (8.75cm x 44.54cm x 74.9cm)
On-Board Devices

  • Intel C621A Chipset
  • Storage Controller

  • HPE Smart Storage SR100i Gen10 Plus SW RAID
  • Intel Virtual RAID on CPU (Intel VROC)
  • Network Controllers

  • Broadcom BCM57412 Ethernet 10Gb 2-port SFP+ OCP3 Adapter for HPE

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Get a quote for HPE ProLiant DL380 Gen10 Plus Server

If you know what you want but can't find the exact configuration you're looking for, have one of our knowledgeable sales staff contact you. Give us a list of the components you would like to incorporate into the system, and the quantities, if more than one. We will get back to you immediately with an official quote.

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